An Active Principle Ingredient is defined as the biologically active component of a medicinal product that is responsible for its intended effect on the human body. This ingredient may be derived from natural sources or synthesized through various chemical processes. The efficacy and safety of a drug largely depend on the characteristics and performance of its API. Therefore, it is critical for manufacturers to ensure that the quality of the API meets stringent standards to guarantee patient safety and treatment effectiveness.
Microbial growth, including bacteria, algae, and fungi, can lead to biofouling, which decreases heat exchange efficiency and can create health risks. Biocides are essential for controlling these organisms. They can be categorized into oxidizing and non-oxidizing types. Oxidizing biocides, such as chlorine and bromine, kill microbes by disrupting their cellular functions, while non-oxidizing biocides, like isothiazolinones, work by inhibiting their growth. Maintaining appropriate biocide levels is crucial for system integrity and compliance with health and safety regulations.